3H-Imidazo[4,5-b]pyridine-6-carboxylic acid, methyl ester
1H-IMidazo[4,5-b]pyridine-6-carboxylic acid, Methyl ester
CAS: 77862-95-4
Molecular Formula: C8H7N3O2
3H-Imidazo[4,5-b]pyridine-6-carboxylic acid, methyl ester - Names and Identifiers
3H-Imidazo[4,5-b]pyridine-6-carboxylic acid, methyl ester - Physico-chemical Properties
| Molecular Formula | C8H7N3O2 |
| Molar Mass | 177.16 |
| Storage Condition | 2-8°C |
3H-Imidazo[4,5-b]pyridine-6-carboxylic acid, methyl ester - Introduction
1H-IMidazo[4,5-b]pyridine-6-carboxylic acid, Methyl ester (1H-IMidazo[4,5-b]pyridine-6-carboxylic acid, Methyl ester) is an organic compound with the formula C10H9N3O2.
Nature:
-Appearance: Colorless to light yellow crystal powder;
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide, dimethylformamide and ethanol, insoluble in water;
-Melting point: about 115-118°C.
Use:
- 1H-IMidazo[4,5-b]pyridine-6-carboxylic acid, Methyl ester is commonly used as a drug intermediate;
-It can be used to synthesize biologically active substances, such as anti-cancer drugs, anti-inflammatory drugs, etc.
Preparation Method:
The synthesis of 1H-IMidazo[4,5-b]pyridine-6-carboxylic acid, Methyl ester is generally carried out through the following steps:
1. firstly, 3-amino -5-pyridine carbonyl chloride is reacted with propionyl formaldehyde to generate 3-amino -5-pyridine methanol;
2. Then, 3-amino -5-pyridine methanol is reacted with methyl aminopropionate to generate 1H-IMidazo[4,5-b]pyridine-6-carboxylic acid, Methyl ester.
Safety Information:
- 1H-IMidazo[4,5-b]pyridine-6-carboxylic acid, Methyl ester is relatively stable under general operating conditions, but it still needs to be handled carefully to avoid inhalation of dust and skin contact;
-in the use of the process, should wear appropriate protective equipment, such as chemical protective gloves, protective glasses and protective masks;
-Store it in a sealed manner, away from fire and oxidant, and avoid prolonged contact with air.
Nature:
-Appearance: Colorless to light yellow crystal powder;
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide, dimethylformamide and ethanol, insoluble in water;
-Melting point: about 115-118°C.
Use:
- 1H-IMidazo[4,5-b]pyridine-6-carboxylic acid, Methyl ester is commonly used as a drug intermediate;
-It can be used to synthesize biologically active substances, such as anti-cancer drugs, anti-inflammatory drugs, etc.
Preparation Method:
The synthesis of 1H-IMidazo[4,5-b]pyridine-6-carboxylic acid, Methyl ester is generally carried out through the following steps:
1. firstly, 3-amino -5-pyridine carbonyl chloride is reacted with propionyl formaldehyde to generate 3-amino -5-pyridine methanol;
2. Then, 3-amino -5-pyridine methanol is reacted with methyl aminopropionate to generate 1H-IMidazo[4,5-b]pyridine-6-carboxylic acid, Methyl ester.
Safety Information:
- 1H-IMidazo[4,5-b]pyridine-6-carboxylic acid, Methyl ester is relatively stable under general operating conditions, but it still needs to be handled carefully to avoid inhalation of dust and skin contact;
-in the use of the process, should wear appropriate protective equipment, such as chemical protective gloves, protective glasses and protective masks;
-Store it in a sealed manner, away from fire and oxidant, and avoid prolonged contact with air.
Last Update：2024-04-09 21:01:54
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Product Name: Methyl 1H-imidazo[4,5-b]pyridine-6-carboxylate Visit Supplier Webpage Request for quotationCAS: 77862-95-4
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Product Name: Methyl 1H-imidazo[4,5-b]pyridine-6-carboxylate Visit Supplier Webpage Request for quotationCAS: 77862-95-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
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WhatsApp: +86-18821248368
Product Name: 1H-IMidazo[4,5-b]pyridine-6-carboxylic acid, Methyl ester Visit Supplier Webpage Request for quotation
CAS: 77862-95-4
Tel: 18301782025
Email: 3008007409@qq.com
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QQ: 3008007409
CAS: 77862-95-4
Tel: 18301782025
Email: 3008007409@qq.com
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View History
3H-Imidazo[4,5-b]pyridine-6-carboxylic acid, methyl ester
Α-甲基-4-(2-甲基丙基)苯乙醛
1,3-Cyclohexadiene-1-carboxylic acid, 2-ethoxy-4-methyl-, ethyl ester
6-碘苯并呋喃-3(2H)-酮
1-Methyl 3-(hydroxymethylphosphinyl)propanoate
5-氨基-1H-吲哚-2-羧酸叔丁酯
Zinc formate
4-Thiazolecarboxylic acid, 2-(2-pyrazinyl)-
1-[3-[[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]METHYL]PHENYL]-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID
5-甲氧基-2-甲基-1H-吲哚-3-羧酸
Α-甲基-4-(2-甲基丙基)苯乙醛
1,3-Cyclohexadiene-1-carboxylic acid, 2-ethoxy-4-methyl-, ethyl ester
6-碘苯并呋喃-3(2H)-酮
1-Methyl 3-(hydroxymethylphosphinyl)propanoate
5-氨基-1H-吲哚-2-羧酸叔丁酯
Zinc formate
4-Thiazolecarboxylic acid, 2-(2-pyrazinyl)-
1-[3-[[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]METHYL]PHENYL]-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID
5-甲氧基-2-甲基-1H-吲哚-3-羧酸